Benefits of Zinc Supplement-Zn+ --Health tips fit - health tips fit

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Saturday, 20 June 2020

Benefits of Zinc Supplement-Zn+ --Health tips fit


 Benefits of zinc supplementation

 Zinc benefits blood sugar control
Diabetes  is a group of chronic metabolic diseases characterized by increased blood glucose levels due to the body's inability to produce insulin or resistance to insulin action.
Due to population growth, aging, urbanization, unhealthy eating habits, obesity, and lack of physical exercise, the prevalence of diabetes  is rising globally.

A systematic literature review and meta-analysis pointed out that zinc supplementation subjects had fasting blood glucose and 2 hours after a meal There were statistically significant reductions in blood glucose, fasting insulin, steady-state model assessment of insulin resistance,  hemoglobin, and high-sensitivity c-reactive protein concentrations.
In addition, subgroup analyses show that the effects of lowering fasting blood glucose are most pronounced in patients with diabetes and those using inorganic zinc supplements.
The underlying mechanism is related to zinc can improve the interaction between insulin receptors, increase the processing rate of glucose and improve glucose tolerance

 Zinc benefits blood pressure regulation
Hypertension is the main risk factor for cardiovascular events and death. Clinically, 69% of the first myocardial infarction, 77% of the first stroke, 74% of heart failure and 60% of peripheral arterial diseases are related to hypertension .
The diagnosis of hypertension is mainly systolic blood pressure of 140 mm Hg or higher, or diastolic blood pressure of 90 mm Hg or higher, affecting about 29% of American adults, and 22% of hypertensive patients do not know that they have disease
A systematic literature review and meta-analysis pointed out that zinc supplementation can significantly reduce systolic blood pressure, but has no significant effect on diastolic blood pressure.
In addition, there was no non-linear correlation between the supplemental dose and time and changes in blood pressure.


Zinc beneficially regulates body weight
Due to the interaction between biological characteristics, behavior and fattening environment, long-term weight management is extremely challenging.
Obesity is an important health problem, because it is easy to cause a variety of , including high blood pressure, , coronary heart disease, type 2 diabetes, stroke, cancer and osteoarthritis, shorten life and reduce life quality
A meta-analysis of literature (including 28 observational studies) pointed out that serum zinc levels in children and adult obese patients were significantly lower.
Another literature meta-analysis (including 27 randomized controlled trials, a total of 1438 participants) pointed out that in the overall analysis, zinc supplementation had no significant effect on any weight-related results.
However, subgroup analysis showed that zinc supplementation increased the weight of homo dialysis patients and reduced the weight of individuals who are overweight/obese but otherwise healthy.


 Zinc benefits male infertility.
Infertility is a common clinical problem. 13% to 15% of couples worldwide are affected by infertility, and about 50% of the causes can be attributed to male factors.
Male factor infertility is characterized by abnormal semen analysis, such as low or missing sperm count, low sperm motility, and the use of any drugs, tobacco, alcohol, or illegal drugs.
After 40 years of age, DNA damage in male sperm will increase significantly, and sperm motility and viability will also decrease.
A systematic literature review and meta-analysis (20 studies, involving 2600 infertile men and 867 normal controls) pointed out that the zinc content in infertile men's seminal plasma was significantly lower than that of normal men. The additional zinc supplementation can significantly increase semen volume, sperm motility, and normal sperm morphology percentage in infertile men.

 Can zinc improve measles?
Measles (Measles) are infections of the respiratory system, immune system, and skin caused by the measles virus. They are highly contagious and vaccine-preventable diseases.
Despite the existence of safe and effective vaccines, measles is still the main cause of global morbidity and mortality, especially in young children, and related complications include pneumonia and encephalitis
The disease is characterized by the appearance of high fever (usually >40°C), Coriolis spots (spots in the mouth, usually appearing 2-3 days before the rash, lasting 3-5 days), discomfort, loss of appetite, red eyes, Runny nose, lethargy, symptoms usually appear 7 to 14 days after exposure to the virus.
Database of Systematic Reviews (including a double-blind randomized controlled trial) pointed out that compared with placebo, oral zinc is necessary to solve the fever and shortness of breath, the time required for appetite recovery, and achieve " The status of "significantly improved" or "cured" did not significantly help.

Zinc strengthens immunity and accelerates recovery from colds.
Cold is the most common self-limiting viral infection in the world. The main symptoms are sneezing, stuffy nose, sore throat, cough, hoarse voice, headache, fever and muscle pain
Most of the current cold treatment methods are mainly to relieve symptoms, but there is no substantial help to fight the cold killer virus.
It is clinically found that zinc is very important for the healthy development of immune cells. If zinc is lacking, it will easily cause abnormal immune function and prone to infection. The potential anti-cold mechanism of zinc (listed below).
Increase the production of antiviral interferon
Prevent viruses from attaching to the respiratory tract
Antiviral proliferation
Inhibits the release of histamine and inflammatory hormones
A meta-analysis of literature (including 3 randomized double-blind trials with a total of 199 participants) pointed out that the use of zinc lozenges (dose between 80-92 mg per day) .

 Zinc reduces the risk of cancer in the digestive tract
The gastrointestinal tract is a term used to define a series of tubular structures and accessory organs, which are involved in the process of digestion and absorption of food intake, and exclude residual waste materials
Any part of the gastrointestinal tract may be affected by malignant tumors. The highest incidence is in the esophagus, stomach, and colon.
A literature review and meta-analysis (including 19 studies with approximately 400,000 participants) pointed out that compared with the group with the lowest zinc intake, the subjects with the highest intake can reduce the risk of gastrointestinal cancer by 18%. In particular, colorectal cancer is the most significant.
Subgroup analysis also found that in Asia, zinc intake was significantly associated with esophageal and gastric cancer risk, but no association was found in the United States and Europe

8. Zinc reduces sore throat after surgery
Postoperative sore throat is mainly caused by tracheal incubation during surgery. It is one of the most common postoperative adverse reactions complained by patients. The incidence rate is about 30% to 70%. The cause is often related to age, gender, smoking, and operation. Technology, diameter, duration, catheter design and intra operative tube movement.
A randomized, double-blind, placebo-controlled study (targeting 79 patients undergoing endotracheal incubation surgery) pointed out that oral zinc tablets (40 mg 30 minutes before surgery) can reduce the incidence and severity of postoperative throat pain.

 Zinc can improve blood lipids
Dyslipidemia is currently recognized as a risk factor for atherosclerosis. It is likely to cause coronary artery disease, cerebrovascular disease and peripheral vascular disease in the long run.
Studies indicate that every 40 mg decrease in low-density lipo-protein cholesterol  can reduce major adverse cardiovascular events by 24%
A systematic literature review and meta-analysis (including 32 studies with a total of 14,515 participants) pointed out that zinc supplementation can help reduce various blood lipid values, including total cholesterol, low-density lipo-protein cholesterol and triglycerides Among them, the improvement of the non-healthy population (obesity, type 2 diabetes, end-stage renal failure and homo dialysis) is the most significant.
The underlying mechanism is related to zinc's ability to improve insulin secretion or reduce insulin resistance, which in turn affects lipid metabolism

 Zinc benefits Parkinson's disease
Parkinson's disease (Parkinson's disease) is a neuro degenerative disease associated with aging. It is estimated that the incidence of about 1% of the global population over 60 years old, the most obvious feature is movement tremor, stiffness, slowness, and posture Stable etc.
Although the main pathogenic mechanism is unknown, inflammation and oxidative stress play an important role, and zinc is an important Cofactor for the formation of various antioxidant enzymes, which has the effect of fighting free radicals and protecting neurons from oxidative damage.
In addition, zinc is an important nutrient in the central nervous system, especially in the hippocampus and cerebral cortex is rich in zinc, if lack of it will affect the balance of the brain, resulting in changes in behavior, learning, memory and emotional stability.
A meta-analysis (23 studies, 1306 cases of Parkinson's disease and 1294 control group) pointed out that compared with healthy people, patients with Parkinson's disease have lower levels of zinc in serum and plasma.
Zinc deficiency is a potential risk factor for Parkinson’s disease, and zinc supplementation may be a potential therapy, pending further studies to confirm its clinical benefit
3 kinds of health foods beneficial to Parkinson's disease.
 Zinc improves tinnitus symptoms.
Tinnitus is mainly defined as the phantom auditory perception caused by no obvious sound stimulation. The prevalence of adults can reach 25.3%, often causing concentration of attention, insomnia, reduced language resolution, and even physical and mental symptoms such as depression and anxiety, affecting life Very high quality.
Observational studies have found that zinc deficiency is often associated with impaired hearing thresholds and the severity of tinnitus loudness.
 Database of Systematic Reviews (contains 3 studies, a total of 209 participants) pointed out that oral zinc has no significant effect on improving tinnitus symptoms in adults (measures include: tinnitus disorder questionnaire, tinnitus Loudness, overall severity).



 Zinc prevents prostate cancer
Prostate cancer is a common malignant tumor disease in men. According to US statistics, it is estimated that about 180,000 new cases are added every year.
Pathological anatomy found that men's risk of getting prostate cancer between 40 and 49 years old is about 40%, and it will increase to 70% between 60 and 69 years old.
The physiological role of zinc in the patho genesis of prostate cancer is not fully elucidated, but the evidence shows that it is related to its ability to inhibit angio genesis and metastasis of cancer cells.
A meta-analysis pointed out that although most prostate cancers have insufficient zinc intake; as of now, the dietary intake of zinc and prostate cancer There is no obvious correlation between the two.
Ingestion of zinc (whether from food or supplements) does not prevent prostate cancer. More large-scale epidemiological studies are needed to further confirm the combined rise in blood glucose levels.
Due to population growth, aging, urbanization, unhealthy eating habits, obesity, and lack of physical exercise, the prevalence of diabetes and pre-diabetes is rising globally.
A systematic literature review and meta-analysis (including 32 randomized placebo-controlled trials with a total of 1700 participants in diabetes and high-risk groups of diabetes) pointed out that zinc supplementation subjects had fasting blood glucose and 2 hours after a meal Control of blood glucose, fasting insulin, steady-state model assessment of insulin resistance, glycated hemoglobin, and highly sensitive c-reactive protein concentrations.

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